Utilizing process-tracing this project bases its analysis on empirical data, specifically primary and secondary sources and semi-structures interviews with activists and decision-makers. The paper compares the framing of goals and network strategies of the first intersex movement (mid-1990’s to about 2000) to the second movement (2005-today). By comparing the two cases the paper isolates the factors that distinguish the successful from the unsuccessful wave of mobilization. It reflects what actors and institutions made a difference during the second wave. One especially important finding is that visibility and important legal reforms in recent years were achieved less by changing movements frames or intersex demands than by building domestic coalitions with more powerful allies and transnational advocacy networks providing access to UN human rights treaties (such as CEDAW). At the UN intersex activists challenged the gender binary by reframing the meaning of their treatment from one of medical “correction” to one of legal and inalienable “protection” of human rights.