This panel addresses questions of governance through analysis of policy impacts of Brexit in the UK. Individual papers analyse the implications of Brexit environmental, fishery and health policies. The fourth paper addresses Brexit’s implications for the UK state as a policy-making structure. Each of the policy analyses is based on current cutting edge research funded by the UK Economic and Social Research Council’s Brexit Priority Grant scheme and conducted by leading scholars, or teams of scholars, in their respective fields. In each policy area, Brexit will reconfigure the relationships among multiple levels of governance. For some papers (for example that on Health), the UK’s future relationship with global regulation is a core focus. Others (such as the Fisheries paper) also analyse new bilateral relations with non-EU members (such as Norway and the Faeroes). Both are currently organised through the EU. Equally the policy fields considered are subject to national devolution to Scotland, Northern Ireland and Wales, with English and UK policy decided at Westminster by the UK government. (‘England only’ laws are now subject to a special ‘English Votes for English Laws’ procedure at Westminster). The EU (Withdrawal) Bill has the potential dramatically to re-centralize legislative and policy power at the Anglo-UK center of Whitehall and Westminster. A second theme addressed by the panel (for example in the Environment paper) is an effectively inevitable territorial restructuring of the UK state as a policymaking system. This panel addresses the challenging issues posed by Brexit for policymaking systems across the UK.